Visual and visuospatial short-term memory in mild cognitive impairment and Alzheimer disease: role of attention.
Neuropsychologia
; 45(8): 1948-60, 2007 Apr 09.
Article
em En
| MEDLINE
| ID: mdl-17275041
ABSTRACT
It has been proposed that visual recognition memory and certain attentional mechanisms are impaired early in Alzheimer disease (AD). Little is known about visuospatial recognition memory in AD. The crucial role of the hippocampus on spatial memory and its damage in AD suggest that visuospatial recognition memory may also be impaired early. The aim of the present study was to evaluate which modality, i.e. visual or visuospatial, is more implicated in the early memory impairment in AD. First, to determine onset of memory impairment, we compared the performances of patients with AD to those with amnestic mild cognitive impairment (MCI). Second, to determine the relative contribution of attentional impairment on the performance of MCI and AD patients, we tested the influence of a distractor in the interval between the memory image and recognition tests. Results showed that visuospatial short-term deficits appear earlier than visual short-term ones. In addition to mnemonic deficits, results showed attentional deficiency in both MCI and AD patients. Deficits of performances in visual modality seemed of attentional origin whereas those of visuospatial modality seemed of memory origin. The combination of attentional and mnemonic evaluation is likely to be a promising approach to finding predictive markers that distinguish MCI patients that convert to AD.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Atenção
/
Percepção Espacial
/
Transtornos Cognitivos
/
Doença de Alzheimer
/
Memória de Curto Prazo
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Neuropsychologia
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
França