Modified lipoproteins as contrast agents for imaging of atherosclerosis.
Contrast Media Mol Imaging
; 2(1): 16-23, 2007.
Article
em En
| MEDLINE
| ID: mdl-17318917
ABSTRACT
The ability to detect and characterize atherosclerosis with targeted contrast agents may enable initiation of therapy for atherosclerotic lesions prior to becoming symptomatic. Since lipoproteins such as high-density lipoprotein (HDL) and low-density lipoprotein (LDL) play a critical role in the regulation of plaque biology through the transport of lipids into and out of atherosclerotic lesions, modifying HDL and LDL with radioisotopes for nuclear imaging, chelates for magnetic resonance imaging (MRI) or other possible contrast agents for computed tomography imaging techniques may aid in the detection and characterization of atherosclerosis. This review focuses on the literature employing lipoproteins as contrast agents for imaging atherosclerosis and the feasibility of this approach.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
/
Aumento da Imagem
/
Tomografia Computadorizada por Raios X
/
Meios de Contraste
/
Aterosclerose
/
Lipoproteínas
Limite:
Humans
Idioma:
En
Revista:
Contrast Media Mol Imaging
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Espanha