[Relationship between lipid peroxidation in blood and neurobehavioral function changes in coke oven workers].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
; 25(1): 15-7, 2007 Jan.
Article
em Zh
| MEDLINE
| ID: mdl-17374181
ABSTRACT
OBJECTIVE:
To explore the coincidence of lipid peroxidation and neurobehavioral function changes in coke oven workers.METHODS:
One hundred and thirty-four coke oven workers were divided into three groups 35 in the oven-bottom group, 49 in the oven-side group and 50 in oven-top group. WHO recommended NCTB was performed on coke oven workers and 36 controls from material conservation department; The contents of total superoxide dismutases (T-SOD), glutathione (GSH) and malondialdehyde (MDA) in blood were determined by test kits.RESULTS:
Compared with the controls, the coke oven workers showed lower levels of T-SOD and GSH (P < 0.01), significantly higher MDA levels in blood (P < 0.01), higher score on negative mood state, lower scores on positive mood state, and poorer performance in NCTB test (P < 0.05). Further analysis revealed that there was a weak positive correlation between neurobehavioral function changes and the level of lipid peroxidation with a coefficient lower than 0.25.CONCLUSION:
The level of lipid peroxidation in coke oven workers' blood increased and coincided with neurobehavioral function impairment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ansiedade
/
Peroxidação de Lipídeos
/
Exposição Ocupacional
/
Afeto
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
Assunto da revista:
MEDICINA OCUPACIONAL
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
China