Interferon-gamma production by African swine fever virus-specific lymphocytes.
Scand J Immunol
; 35(2): 225-30, 1992 Feb.
Article
em En
| MEDLINE
| ID: mdl-1738818
ABSTRACT
Peripheral blood mononuclear cells (PBMC) from inbred pigs that were immunized with autologous macrophages infected with the African swine fever (ASF) virus BA71V, a nonvirulent virus isolate, proliferated and produced interleukin-2 in response to homologous and heterologous isolates of the ASF virus. They produced, however, interferon (IFN) only when challenged in vitro with homologous or attenuated isolates of the ASF virus, but not with heterologous or virulent isolates. The IFN was pH 2 labile and was neutralized by specific serum to porcine recombinant IFN gamma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Interferon gama
/
Vírus da Febre Suína Africana
Limite:
Animals
Idioma:
En
Revista:
Scand J Immunol
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Espanha
País de publicação:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM