Fractionated treatment of CaD2 tumors in mice sensitized with aluminium phthlocyanine tetrasulfonate.
Cancer Lett
; 61(3): 263-7, 1992 Jan 31.
Article
em En
| MEDLINE
| ID: mdl-1739951
ABSTRACT
CaD2 mammary carcinomas transplanted into the feet of mice were treated with tetrasulfonated phthalocyanine (AlPcS4) and laser light at 680 nm. A light dose of 135 J/cm2 was either given as continuous radiation (15 min) or fractionated with 15 s exposure, 15 s darkness, 15 s exposure and so on for 30 min. The CaD2 tumors were found to respond better to a fractionated exposure than to the same energy given in one exposure. The reason for this is assumed to be a relocalization of the dye upon illumination, seen as a rapid decrease in fluorescence. When the laser light was turned off, the fluorescence returned to almost the initial value.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
/
Fotoquimioterapia
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Radiossensibilizantes
/
Indóis
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Neoplasias Mamárias Experimentais
Limite:
Animals
Idioma:
En
Revista:
Cancer Lett
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Noruega