[Pulmonary infections with Mycobacterium xenopi in patients without HIV infection]. / Les infections pulmonaires à Mycobacterium xenopi en dehors du VIH/SIDA: étude rétrospective sur dix cas.
Rev Mal Respir
; 24(3 Pt 1): 299-304, 2007 Mar.
Article
em Fr
| MEDLINE
| ID: mdl-17417167
ABSTRACT
OBJECTIVE:
To determine the incidence, clinical characteristics, microbiological features and outcome of Mycobacterium xenopi infections in patients attending a university hospital.METHODS:
We reviewed the files of HIV-seronegative patients meeting ATS criteria for M. xenopi pulmonary infection between 1993 and 2004.RESULTS:
Ten patients were studied (7 men, 60+/-27 years). All but one had underlying chronic health disorders (chronic lung disease, cancer, alcoholism, systemic steroid therapy). The clinical and radiological findings were those associated with tuberculosis. Acid-fast bacilli were detected by direct examination in 9 cases, and antituberculous treatment prescribed in 8 patients. Specific treatment was started an average of 60+/-25 days after sampling, and generally combined a fluoroquinolone, clarithromycin and rifampicin, with or without ethambutol, for a mean of 11.4 months (1-37 months). Five patients had surgical excision (diagnostic in 1 case). Four patients died of their underlying disease. Two patients recovered with antibiotics alone and three with antibiotics and surgery. One patient was lost to follow-up after five months.CONCLUSION:
Pulmonary infection by M. xenopi is rare in HIV-seronegative patients. The prognosis depends mainly on the patient's underlying health status. Surgery is an important component of treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tuberculose Pulmonar
/
Mycobacterium xenopi
/
Infecções por Mycobacterium não Tuberculosas
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Patient_preference
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Fr
Revista:
Rev Mal Respir
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
França