Transplantation of the hand, face, and composite structures: evolution and current status.
Clin Plast Surg
; 34(2): 271-8, ix-x, 2007 Apr.
Article
em En
| MEDLINE
| ID: mdl-17418676
ABSTRACT
This article reviews the world experience in the newly emerging field of composite tissue allotransplantation. These allografts contain multiple tissues that are usually musculoskeletal structures with a skin or epithelial surface, such as hand, facial structures, larynx, tongue, ear, knee/femur, abdominal wall, and penis. They represent a new transplantation field, with only a 10-year experience and just over 50 clinical cases. This review of the 10-year world experience found uniform technical success, immunologic biology, and immunosuppression regimens very similar to solid organ transplants, and success strongly correlated with adherence to guidelines for psychiatric screening, thorough preparation of patient and families, intense postoperative monitoring, and assurance of medication access. All failures reported have been caused by lapses in these parameters. This early experience shows a great potential for application of these new procedures to the most challenging reconstructive needs.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante Homólogo
/
Transplante de Tecidos
/
Face
/
Transplante de Mão
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
Clin Plast Surg
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos