Altered expression of plant lysyl tRNA synthetase promotes tRNA misacylation and translational recoding of lysine.
Plant J
; 50(4): 627-36, 2007 May.
Article
em En
| MEDLINE
| ID: mdl-17425721
ABSTRACT
The Arabidopsis thaliana lysyl tRNA synthetase (AtKRS) structurally and functionally resembles the well-characterized prokaryotic class IIb KRS, including the propensity to aminoacylate tRNA(Lys) with suboptimal identity elements, as well as non-cognate tRNAs. Transient expression of AtKRS in carrot cells promotes aminoacylation of such tRNAs in vivo and translational recoding of lysine at nonsense codons. Stable expression of AtKRS in Zea mays causes translational recoding of lysine into zeins, significantly enriching the lysine content of grain.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
RNA de Transferência de Lisina
/
Arabidopsis
/
Lisina
/
Lisina-tRNA Ligase
Idioma:
En
Revista:
Plant J
Assunto da revista:
BIOLOGIA MOLECULAR
/
BOTANICA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos