[Pharmacotherapeutic aspects of femoral head necrosis]. / Pharmakotherapeutische Aspekte der Femurkopfnekrose.
Orthopade
; 36(5): 446-50, 2007 May.
Article
em De
| MEDLINE
| ID: mdl-17476478
ABSTRACT
Avascular necrosis (AVN) of the hip is one of the unsolved problems in orthopedics, especially with regard to drug therapy. Only a few studies exist using a long-term approach with vasodilating agents such as prostaglandins, anticoagulants, hormones, as well as lipid lowering and bone protective drugs such as bisphosphonates. However, using these medications several studies have demonstrated a significant reduction in pain, in the destruction of the femoral head as well as in overall disability. This resulted in a reduced need for joint replacement in patients with AVN and to a substantial improvement in quality of life. Of note, drug therapy should be initiated in the early phases of AVN as later stages appear to be less responsive to medication.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vasodilatadores
/
Artralgia
/
Difosfonatos
/
Conservadores da Densidade Óssea
/
Necrose da Cabeça do Fêmur
/
Hipolipemiantes
Tipo de estudo:
Etiology_studies
Aspecto:
Patient_preference
Limite:
Humans
Idioma:
De
Revista:
Orthopade
Ano de publicação:
2007
Tipo de documento:
Article