Scophedal (SEE) was it a fad or a miracle drug?
Bull Anesth Hist
; 21(4): 12-4, 2003 Oct.
Article
em En
| MEDLINE
| ID: mdl-17494237
The German firm E. Merck released in 1928, an injectable mixture of scopolamine, oxycodone, and ephedrine under the name SEE. This drug, renamed Scophedal in 1942 caused deep and prolonged analgesia, sedation, euphoria and amnesia without significant respiratory or circulatory depression. Used extensively by the German and Central European surgeons in the 1930s, Scophedal enjoyed immense popularity with the Wehrmacht's medical officers treating frontline mass casualties during World War II. The use of Scophedal declined after 1945, and its production was discontinued in 1987. Despite the clinical enthusiasm it raised, SEE was never critically investigated. This drug may deserve a rigorous re-evaluation.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Simpatomiméticos
/
Analgésicos Opioides
/
Anestesia
Limite:
Humans
Idioma:
En
Revista:
Bull Anesth Hist
Assunto da revista:
ANESTESIOLOGIA
/
HISTORIA DA MEDICINA
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Estados Unidos
País de publicação:
Estados Unidos