False-negative prenatal exclusion of Wiskott-Aldrich syndrome by measurement of fetal platelet count and size.
Prenat Diagn
; 11(11): 819-25, 1991 Nov.
Article
em En
| MEDLINE
| ID: mdl-1754554
ABSTRACT
The study of the fetal platelet count and size can, according to the literature, be used for the prenatal diagnosis of the Wiskott-Aldrich syndrome (WAS). So far, no affected fetuses have been identified by this method. All pregnancies in which this method had been applied to resulted, as correctly predicted, in the birth of normal children. Here we report on a familial case of WAS where the haematological parameters failed to reveal the affected second child. Hence we assume that the platelet count and size of platelets remain normal in fetuses with WAS to the gestational age of 22 weeks and cannot be used for prenatal diagnosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Contagem de Plaquetas
/
Diagnóstico Pré-Natal
/
Síndrome de Wiskott-Aldrich
/
Plaquetas
/
Sangue Fetal
/
Doenças Fetais
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Prenat Diagn
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Alemanha