Bruising at birth: antenatal associations and neonatal outcome of extremely low birth weight infants.
Neonatology
; 92(4): 258-63, 2007.
Article
em En
| MEDLINE
| ID: mdl-17556844
ABSTRACT
BACKGROUND:
Early studies have identified severe cranial bruising as a risk factor for intraventricular hemorrhage (IVH) in premature infants but the nature of this association has not been evaluated.OBJECTIVE:
To identify antenatal predictors and associations with neonatal outcome of bruised extremely low birth weight infants.METHODS:
A cohort study comparing 34 bruised and 116 non-bruised infants (birth weightRESULTS:
In a stepwise logistic regression on 'Any bruising' and 'Severe bruising', only increasing gestational age and exposure to antenatal steroids prior to delivery maintained a protective association with bruising (OR = 0.74; 95% CI 0.58-0.94; p = 0.015, OR = 0.38; 95% CI 0.16-0.90; p = 0.028, respectively, for 'Any bruising', and OR = 0.77; 95% CI 0.59-1.01; p = 0.055, OR = 0.29; 95% CI 0.12-0.73; p = 0.008, respectively, for 'Severe bruising'). In a stepwise logistic regression analysis, with 'Any bruising' and 'Severe bruising' as forced-in variables and controlling for gestational age, small for gestational age, Apgar scores, respiratory distress syndrome and pneumothorax, 'Severe bruising', but not 'Any bruising', was found to be associated significantly with severe IVH (OR = 5.60; 95% CI 1.86-16.82; p = 0.002), whereas both 'Any bruising' and 'Severe bruising' were significantly associated with mortality (OR = 6.31; 95% CI 2.37-16.83; p = 0.000, OR = 3.33; 95% CI 1.16-9.52; p = 0.025 respectively).CONCLUSION:
Antenatal exposure to steroids and increasing gestational age are associated with a lower incidence of bruising at birth in extremely low birth weight infants. Severe bruising at birth is associated with increased incidence of severe intraventricular hemorrhage and mortality.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Traumatismos do Nascimento
/
Resultado da Gravidez
/
Hemorragia Cerebral
/
Contusões
/
Recém-Nascido de Peso Extremamente Baixo ao Nascer
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Neonatology
Assunto da revista:
PERINATOLOGIA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Israel