Acetylated pseudoguaianolides from Parthenium hysterophorus and their cytotoxic activity.
Phytochemistry
; 68(15): 2029-34, 2007 Aug.
Article
em En
| MEDLINE
| ID: mdl-17570445
ABSTRACT
Chemical examination of the flowers of Parthenium hysterophorus has resulted in the isolation of four acetylated pseudoguaianolides along with several known constituents. The structures of the compounds were derived from detailed studies of their spectral (1D and 2D NMR and FABMS) data and by comparison of the values with those of parthenin, a major known constituent of the plant. The cytotoxic activity of parthenin and the constituents was evaluated using Jurkat (human T lymphocyte; acute T cell leukemia), HL-60 (human leukemia) and Hela (human cervical carcinoma) cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extratos Vegetais
/
Asteraceae
/
Sesquiterpenos de Guaiano
/
Antineoplásicos Fitogênicos
Limite:
Humans
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Índia