[Response to tamoxifen in estrogen receptor-positive cell line MCF-7 is independent of p53 expression].
Vopr Onkol
; 53(2): 194-9, 2007.
Article
em Ru
| MEDLINE
| ID: mdl-17663174
ABSTRACT
The study was concerned with identification of predictive value of p53 expression on sensitivity to tamoxifen in breast cancer management. Estrogen receptor-positive cell line MCF-7 was used to establish p53 expression influence on the rate of cell proliferation after tamoxifen. The investigation demonstrated the absence of that effect when p53 was silenced.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tamoxifeno
/
Neoplasias da Mama
/
Receptores de Estrogênio
/
Proteína Supressora de Tumor p53
/
Antineoplásicos Hormonais
/
Moduladores de Receptor Estrogênico
Limite:
Female
/
Humans
Idioma:
Ru
Revista:
Vopr Onkol
Ano de publicação:
2007
Tipo de documento:
Article