Gaussian prefiltering of 123I DAT SPECT images when using depth-independent resolution recovery.
Phys Med Biol
; 52(18): N393-9, 2007 Sep 21.
Article
em En
| MEDLINE
| ID: mdl-17804873
ABSTRACT
Previously we have investigated a depth-independent compensation for collimator detector response (CDR) included in the OSEM reconstruction, intended for SPECT images that have been corrected for scatter and septal penetration using convolution-based methods. In this work, the aim was to study how different filtering strategies affect contrast as a function of noise when using Gaussian smoothing filters in combination with the above-described CDR compensation. The evaluation was performed for (123)I dopamine transporter (DAT) SPECT images. Prefiltering with 2D Gaussian filter kernels, where the deterioration in resolution is included in the depth-independent CDR compensation, was compared to conventional postfiltering with 3D Gaussian filter kernels. Images reconstructed without filtering are also included in the comparison. It was found that there is little benefit in noise reduction when using CDR compensation. However, this variant of prefiltering gives consistently higher contrasts as a function of noise compared with the postfiltering alternative, and that could be of interest when using other types of filters with contrast improving properties.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Algoritmos
/
Encéfalo
/
Interpretação de Imagem Assistida por Computador
/
Aumento da Imagem
/
Tomografia Computadorizada de Emissão de Fóton Único
/
Proteínas da Membrana Plasmática de Transporte de Dopamina
/
Radioisótopos do Iodo
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
Limite:
Humans
Idioma:
En
Revista:
Phys Med Biol
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Suécia