Is intravenous lidocaine clinically effective in acute migraine?
Cephalalgia
; 11(6): 245-7, 1991 Dec.
Article
em En
| MEDLINE
| ID: mdl-1790567
ABSTRACT
We performed a prospective, randomized, double-blind, placebo-controlled trial of intravenous lidocaine (1 mg/kg) in the treatment of acute migraine. Thirteen subjects were randomly allocated to receive intravenous lidocaine and 12 received intravenous normal saline. Subjects scored the intensity of headache and nausea on separate visual analogue scales before the injection and at 10 and 20 min after injection. At 20 min, the mean pain intensity score was 80% of initial intensity in the lidocaine group and 82% in the placebo group. The difference was not statistically significant; at 20 min, the 95% confidence interval for the difference between the two groups in mean percentage of initial pain score was 2 +/- 29%. At the dose studied, intravenous lidocaine has, at best, only a modest effect in acute migraine.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lidocaína
/
Transtornos de Enxaqueca
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Cephalalgia
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Austrália