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Effects of K. lysolecithin on blood levels of monoamines in mice.
Itokwa, Yuka; Kozu, Aki; Nakamura, Takashi; Masubuchi, Takashi; Oshima, Masami; Cho, Kwang-Ho; Choi, Jung-Sook; Miura, Toshihiro; Ishida, Torao; Gu, Yeunhwa.
Afiliação
  • Itokwa Y; Suzuka Univercity of Medical Science, Graduate School of Health Science, 510-0293, Japan.
J Tradit Chin Med ; 27(3): 212-9, 2007 Sep.
Article em En | MEDLINE | ID: mdl-17955661
In this research, Lysolecithin - a substance made with 100% natural ingredients - was given to ICR mice as medication to measure its periodic effect on the noradrenalin (NA), dopamine (DA), and serotonin (5-HT) levels of the brain. Both ICR and SAM mice were separated into two groups - control group and Lysolecithin (K. Lysolecithin: hydrolytic lysolecithin) medicated group, and given 1-week preparation period. The K. Lysolecithin group was given 500 mg/kg of K. Lysolecithin at 0.2 mL per dosage for 4 weeks, and the control group was given the same amount of dosage of water during the same period. NA, DA and 5-HT concentrations were measured from the blood before medication and 8 weeks/12 weeks/16 weeks after the first medication. For the SAM mice, 8 weeks after they were medicated with K .Lysolecithin, Morris Water Maze Test was conducted for 7 consecutive days and then the concentrations were measured by drawing blood from the heart. The K. Lysolecithin medicated group showed a tendency to have a statistically significant higher concentrations of 5-HT and NA in the blood. Also, periodic examination showed that the monoamine levels were highest in the 12th week and declined thereafter.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lisofosfatidilcolinas / Monoaminas Biogênicas / Doença de Alzheimer Tipo de estudo: Clinical_trials Limite: Animals / Humans / Male Idioma: En Revista: J Tradit Chin Med Ano de publicação: 2007 Tipo de documento: Article País de afiliação: Japão País de publicação: China
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lisofosfatidilcolinas / Monoaminas Biogênicas / Doença de Alzheimer Tipo de estudo: Clinical_trials Limite: Animals / Humans / Male Idioma: En Revista: J Tradit Chin Med Ano de publicação: 2007 Tipo de documento: Article País de afiliação: Japão País de publicação: China