Effects of K. lysolecithin on blood levels of monoamines in mice.
J Tradit Chin Med
; 27(3): 212-9, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-17955661
In this research, Lysolecithin - a substance made with 100% natural ingredients - was given to ICR mice as medication to measure its periodic effect on the noradrenalin (NA), dopamine (DA), and serotonin (5-HT) levels of the brain. Both ICR and SAM mice were separated into two groups - control group and Lysolecithin (K. Lysolecithin: hydrolytic lysolecithin) medicated group, and given 1-week preparation period. The K. Lysolecithin group was given 500 mg/kg of K. Lysolecithin at 0.2 mL per dosage for 4 weeks, and the control group was given the same amount of dosage of water during the same period. NA, DA and 5-HT concentrations were measured from the blood before medication and 8 weeks/12 weeks/16 weeks after the first medication. For the SAM mice, 8 weeks after they were medicated with K .Lysolecithin, Morris Water Maze Test was conducted for 7 consecutive days and then the concentrations were measured by drawing blood from the heart. The K. Lysolecithin medicated group showed a tendency to have a statistically significant higher concentrations of 5-HT and NA in the blood. Also, periodic examination showed that the monoamine levels were highest in the 12th week and declined thereafter.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lisofosfatidilcolinas
/
Monoaminas Biogênicas
/
Doença de Alzheimer
Tipo de estudo:
Clinical_trials
Limite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
J Tradit Chin Med
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Japão
País de publicação:
China