[Blood plasma diene conjugates during the stimulation and inhibition of lipid peroxidation in dogs with different forms of healing in experimental myocardial infarct]. / Dienovye kon''iugaty plazmy krovi pri stimuliatsii i ingibirovanii perekisnogo okisleniia lipidov u sobak s razlichnymi formami zazhivleniia éksperimental'nogo infarkta miokarda.
Patol Fiziol Eksp Ter
; (4): 37-8, 1991.
Article
em Ru
| MEDLINE
| ID: mdl-1798651
ABSTRACT
In experiments on 45 dogs with a model of normo-, hyper-, and hyporeactive myocardial infarction, (MI) lipid peroxidation (LP) was stimulated by ultraviolet irradiation of autologous blood and inhibited by alpha-tocopherol acetate. It is shown that changes of LP are characteristic of uncomplicated healing of normoreactive MI. Hyperactivation of LP in hyperreactive MI and its hypoactivation in hyporeactive MI are among the factors of complication of its healing by postinfarction aneurysm of the heart. LP modulation consisting in bringing its changes in conformity with those in uncomplicated forms of the disease facilitates normal MI healing with the formation of a postinfarction scar. Antioxidants are indicated in hyperreactive MI, and LP activation by means of stimulators is recommended in hyporeactive MI.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cicatrização
/
Peroxidação de Lipídeos
/
Alfa-Tocoferol
/
Peróxidos Lipídicos
/
Infarto do Miocárdio
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
Ru
Revista:
Patol Fiziol Eksp Ter
Ano de publicação:
1991
Tipo de documento:
Article