Hydroxyapatite nanoparticle loaded collagen fiber composites: microarchitecture and nanoindentation study.
J Biomed Mater Res A
; 86(4): 873-82, 2008 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-18041734
ABSTRACT
Hydroxyapatite (HA) nanoparticle-collagen composite materials with various HA/collagen weight ratios were prepared from HA/collagen dispersions using the solution deposition and electrospinning with static or rotating collectors. The composites with nanoparticle HA to collagen weight ratio of 8020 can be easily prepared in the solution deposition approach, whereas in the electrospun fibrous composites it was possible to reach a maximum HA/collagen weight ratio of 3070 while maintaining a good fibrous structure. The structure, surface morphology, and nanoindentation properties of these nanoparticle HA/collagen composites with different microarchitectures were investigated. The values from 0.2 GPa to 20 GPa for nanoindentation Young's modulus and from 25 MPa to 500 MPa for hardness, were obtained depending on the fabrication technique, composition, and microarchitecture of the composites. It was observed that the nanoindentation Young's modulus and hardness of the HA/collagen composite materials seem to achieve maximum values for 45-60% HA content by weight.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Teste de Materiais
/
Colágeno
/
Durapatita
/
Nanocompostos
/
Nanopartículas
Idioma:
En
Revista:
J Biomed Mater Res A
Assunto da revista:
ENGENHARIA BIOMEDICA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos