Cardiovascular and metabolic responses to catecholamine and sepsis prognosis: a ubiquitous phenomenon?
Crit Care
; 12(2): 118, 2008.
Article
em En
| MEDLINE
| ID: mdl-18394178
ABSTRACT
Many parameters have been associated with sepsis prognosis. In the present issue of Critical Care, Kumar and colleagues demonstrate that a preserved cardiac answer to dobutamine evaluated by radionucleotide measurements was associated with a better prognosis during septic shock. In this context, it is interesting to note that not only is the cardiac response to catecholamine stimulation associated with prognosis, but also the vascular and metabolic responses are associated. The ability of exogenous catecholamine to increase the arterial pressure (dopamine test) or to increase the lactate level is also related to prognosis. According to the ubiquitous character of catecholamine sensitivity, therefore, we should think in terms of cellular ability to respond to catecholamines in defining the concept of physiological reserve.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Choque Séptico
/
Cardiotônicos
/
Função Ventricular Esquerda
/
Sepse
/
Dobutamina
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Crit Care
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
França