Environmental risk factors for relapse of melanoma.
Eur J Cancer
; 44(12): 1717-25, 2008 Aug.
Article
em En
| MEDLINE
| ID: mdl-18602256
ABSTRACT
AIM:
To identify lifestyle factors affecting risk of relapse.METHODS:
A comparison of 131 relapsed melanoma patients with 147 non-relapsers.RESULTS:
Relapsers were more likely to report financial hardship using a number of different measures including access to holidays and feeling financially insecure (odds ratio (OR) 5.7, 95% confidence interval (CI) (1.5, 21.4)). Relapsers worked longer hours (mean 37h per week compared with 31, p=0.02). There was no reported difference in stress associated with recent life events. There was no effect of housing quality, employment factors or body mass index (BMI) on risk of relapse. There was a protective effect of antibiotics in the peri-operative period.CONCLUSION:
The study provides preliminary evidence for adverse effects of chronic financial hardship, but not recent stressful events on cancer relapse. As these data were collected in a retrospective case-control study subject to recall bias, the data must now be explored in a prospective study.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estresse Psicológico
/
Melanoma
/
Recidiva Local de Neoplasia
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur J Cancer
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Reino Unido