Are the Basques a single and a unique population?
Am J Hum Genet
; 49(2): 450-8, 1991 Aug.
Article
em En
| MEDLINE
| ID: mdl-1867201
ABSTRACT
Different analyses of genetic polymorphisms performed on the Basque population have suggested a possible heterogeneity of the Basques and a singularity of their genetic characteristics. In this paper, both aspects are analyzed by means of the genetic study of seven polymorphic systems--ACP, ADA, AK, ESD, PGD, GC, and HP--in 854 autochthonous individuals from the province of Vizcaya. The individuals were classified as being from the regions of Arratia, Guernica, Durango, Uribe, Marquina, Lea, and Bilbao, on the basis of the birthplaces of their four grandparents. Analyses for heterogeneity of the gene frequencies distribution suggest that there is a moderate genetic heterogeneity, probably produced by centuries of geographical and administrative isolation of these regions. The comparison with caucasoid populations, performed using the principal components analysis and Cavalli-Sforza and Edwards arc distance, indicates that the subpopulations of the province of Vizcaya have experienced little genetic exchange with other caucasoids and that the distribution of their genetic frequencies differentiates them from other populations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Etnicidade
/
Frequência do Gene
/
Isoenzimas
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Am J Hum Genet
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Espanha