Elastin and collagen content in the aorta of rabbits experimentally immunized with soluble elastin.

ABSTRACT

Experimental immunization of rabbits with soluble porcine elastin was performed. A statistically significant decrease in the level of insoluble elastin in the aorta of the immunized animals was observed. Estimations of soluble collagen fractions showed the rise of both salt-soluble and acid-soluble collagen in the aorta of rabbits immunized with soluble porcine elastin.