[The isolation and characteristics of reassortants between the Lassa and Mopeia arenaviruses]. / Poluchenie i kharakteristika reassortantov mezhdu arenavirusami Lassa i Mopeiia.
Vopr Virusol
; 36(2): 146-50, 1991.
Article
em Ru
| MEDLINE
| ID: mdl-1882522
ABSTRACT
Reassortants with a mixed phenotype were produced by combined inoculation of Vero cells with Lassa and Mopeya viruses. These reassortants produced small plaques (Mopeya virus phenotype) and were not pathogenic for newborn mice (Lassa virus phenotype). The genotype of the reassortants was studied by dot hybridization experiments on filters using cDNA-probes differentiating genome segments of these viruses. The reassortants were shown to have Mopeya virus L-RNA and Lassa virus S-RNA.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arenaviridae
/
Recombinação Genética
/
Vírus Lassa
Limite:
Animals
Idioma:
Ru
Revista:
Vopr Virusol
Ano de publicação:
1991
Tipo de documento:
Article