Endometrial polyps and associated factors in Danish women aged 36-74 years.
Am J Obstet Gynecol
; 200(2): 147.e1-6, 2009 Feb.
Article
em En
| MEDLINE
| ID: mdl-18992861
ABSTRACT
OBJECTIVE:
To identify factors associated with endometrial polyps. STUDYDESIGN:
Case-control study of 140 women with endometrial polyps and 367 controls. Information on potentially associated factors was obtained by a validated questionnaire.RESULTS:
In an age-adjusted logistic regression model, the following was positively associated with endometrial polyps current use of hormone therapy (odds ratio, 2.81; 95% CI, 1.29-6.13) and being overweight (body mass index > 25 kg/m(2)) (odds ratio, 2.06; 95% CI, 1.12-3.79) (postmenopausal women). Negatively associated was use of oral contraceptive pills (odds ratio, 0.20; 95% CI, 0.06-0.66). Histopathology diagnosed benign endometrial polyps (n = 137), polyp with premalignant disease (n = 3), and benign polyp with concomitant complex hyperplasia/endometrial cancer (n = 3).CONCLUSION:
Being overweight and current use of hormone therapy in postmenopausal women were positively associated, whereas the use of oral contraceptive pills was negatively associated with endometrial polyps. Hypertension and cervical polyps were not associated with endometrial polyps. Endometrial polyps were infrequently related to premalignant and malignant disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Endométrio
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Am J Obstet Gynecol
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Dinamarca