[Axon and Schwann cells... so far away, so close]. / Axones et cellules de Schwann... si loin, si proches.
Rev Neurol (Paris)
; 164(12): 1057-62, 2008 Dec.
Article
em Fr
| MEDLINE
| ID: mdl-19041107
ABSTRACT
Myelination was a major step in the evolution of the nervous system. Appearing first in jaw fish, myelination allows the fast and secure propagation of action potentials at a low energetic cost, and without exaggerated increase in axonal diameter. In the peripheral nervous system of mammals, myelination results from the tight interactions between Schwann cells and axons, leading to the formation of highly differentiated domains along the axon. The molecular determinants of these interactions are starting to be well identified. Their understanding provides a precise framework to interpret the defects, which occur in pathological circumstances. This review summarizes the present state of knowledge concerning axoglial interactions in peripheral nerves.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células de Schwann
/
Axônios
Limite:
Animals
/
Humans
Idioma:
Fr
Revista:
Rev Neurol (Paris)
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
França