A preparatively convenient ligand-free catalytic PEG 2000 Suzuki-Miyaura coupling.
J Org Chem
; 74(3): 1381-4, 2009 Feb 06.
Article
em En
| MEDLINE
| ID: mdl-19178357
ABSTRACT
A ligand-free Suzuki-Miyaura reaction for the cross-coupling of aryl and heteroaryl bromides with aryl and heteroarylboronic acids has been developed utilizing catalytic polyethylene glycol 2000 (PEG 2000). This preparatively convenient system afforded the corresponding cross-coupled products in good to excellent isolated yields after a simple aqueous workup. Transmission electron microscopy (TEM) analysis of the Pd-PEG 2000 catalyst system revealed in situ-generated palladium nanoparticles after only 1 min of reaction.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polietilenoglicóis
/
Compostos de Bifenilo
/
Ácidos Borônicos
/
Bromobenzenos
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Estados Unidos