Rabies in Thailand: 1990.
Rev Infect Dis
; 13(4): 644-52, 1991.
Article
em En
| MEDLINE
| ID: mdl-1925286
ABSTRACT
Of the more than 100,000 courses of postexposure rabies treatment given in Thailand annually, 95% consist of brain tissue-derived vaccine without immune globulin. Rabies tissue culture vaccines and immune globulins are expensive by the standards of developing countries. When they are given according to either of two proven intradermal postexposure schedules, significant savings can be achieved without loss of efficacy. Purified equine rabies immune globulins account for approximately 10% of the cost of human products administered to exposed individuals and have been shown to be safe and effective. A canine preexposure immunogenicity study with a potent, inactivated tissue culture vaccine revealed that 12.5% of Thai dogs failed to develop protective antibody titers 2 months after one subcutaneous injection. Previous studies have shown significant antigenic differences between Thai street rabies virus and European and North African strains.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Raiva
/
Vacina Antirrábica
/
Imunização Passiva
/
Doenças do Cão
Tipo de estudo:
Guideline
Limite:
Animals
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Rev Infect Dis
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Tailândia