Neuropeptides in cutaneous neurofibromas of von Recklinghausen's disease.
J Cutan Pathol
; 17(6): 371-3, 1990 Dec.
Article
em En
| MEDLINE
| ID: mdl-1981573
ABSTRACT
The occurrence of neuropeptides was studied in neurofibromas of von Recklinghausen's disease by indirect immunofluorescence. All non-plexiform cutaneous neurofibromas contained abundant vasoactive intestinal polypeptide, peptide histidine-isoleucine and calcitonin gene-related peptide immunoreactive nerves. The nerves were small and unmyelinated. Neuropeptides might be responsible for itch that occurs especially in small cutaneous neurofibromas. Neuropeptides are also suggested to act as modulators and/or trophic factors for neurofibroma growth.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Neuropeptídeos
/
Neurofibromatose 1
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Cutan Pathol
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
Finlândia