Trisomy 5 in Ph+ chronic myeloid leukemia in association with megakaryocytosis.
Cancer Genet Cytogenet
; 51(2): 273-5, 1991 Feb.
Article
em En
| MEDLINE
| ID: mdl-1993312
ABSTRACT
A patient with a megakaryocytosis associated with a Philadelphia chromosome-positive chronic myeloid leukemia (CML) was found to have a trisomy of chromosome five. To our knowledge, this is the first case of trisomy 5 associated with a Ph + CML, particularly one with a megakaryocytosis. The trisomy 5 may be associated with the resistance to cytostatic drugs found in this patient.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trissomia
/
Cromossomos Humanos Par 5
/
Megacariócitos
/
Leucemia Mielogênica Crônica BCR-ABL Positiva
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cancer Genet Cytogenet
Ano de publicação:
1991
Tipo de documento:
Article