Identification of the ancestral haplotype for apolipoprotein B suggests an African origin of Homo sapiens sapiens and traces their subsequent migration to Europe and the Pacific.
Proc Natl Acad Sci U S A
; 88(4): 1403-6, 1991 Feb 15.
Article
em En
| MEDLINE
| ID: mdl-1996341
ABSTRACT
The probable ancestral haplotype for human apolipoprotein B (apoB) has been identified through immunological analysis of chimpanzee and gorilla serum and sequence analysis of their DNA. Moreover, the frequency of this ancestral apoB haplotype among different human populations provides strong support for the African origin of Homo sapiens sapiens and their subsequent migration from Africa to Europe and to the Pacific. The approach used here for the identification of the ancestral human apoB haplotype is likely to be applicable to many other genes.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apolipoproteínas B
/
Haplótipos
/
Hominidae
/
Evolução Biológica
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
/
Humans
País/Região como assunto:
Africa
/
Asia
/
Europa
/
Oceania
Idioma:
En
Revista:
Proc Natl Acad Sci U S A
Ano de publicação:
1991
Tipo de documento:
Article