[Heart injury caused by air shock wave trauma]. / Obrazenia serca spowodowane przez bezposrednie dzialanie powietrznej fali underzeniowej.

ABSTRACT

The aim of the study was the estimation of heart muscle in response to air shock wave trauma. The animals were divided into four groups according to the time between trauma and the examination (3, 24, 48 and 120 hours). In all groups of animals ecg was performed and plasma level of creatinine kinase (CK), cardiac isoenzymes (CK-MB), lactic dehydrogenase (LDH) and its isoenzymes (LDH1-2) and alpha hydroxybutyrate dehydrogenase (HBDH) were determined. CK-MB activity as a percent of CK activity and rate of LDH isoenzymes activity were calculated. Morphologic estimation of heart injury based on macroscopic observation, histology and coronarography of heart specimens was performed. It was revealed that pathologic changes in ecg indicating intracardial conduction disturbances occur most intensively in first ten minutes after trauma. Plasma CPK, LDH and LDH1-2 activity increased significantly after 120 hrs following trauma. Morphologic manifestation of heart damage was multifocal injury of heart muscle.