Resting-state EEG gamma activity in children with attention-deficit/hyperactivity disorder.
Clin Neurophysiol
; 121(11): 1871-7, 2010 Nov.
Article
em En
| MEDLINE
| ID: mdl-20483659
ABSTRACT
OBJECTIVE:
Children with Attention-Deficit/Hyperactivity Disorder (AD/HD) have well-described abnormalities in the four traditional EEG bands. However, to date the gamma band has not been widely investigated. This study investigated resting-state EEG in children with AD/HD and matched controls, with a particular focus on gamma activity.METHOD:
Forty children with AD/HD, and 40 age- and sex-matched controls, participated. EEG was recorded from 19 sites during an eyes-closed resting condition and Fourier transformed to provide estimates for absolute and relative power in the delta, theta, alpha, beta and gamma bands.RESULTS:
Children with AD/HD had elevated levels of absolute delta and theta power, and decreased levels of absolute beta and gamma power, compared to controls. With relative power measures, children with AD/HD showed enhanced delta and theta activity, with reduced alpha, beta and gamma activity. Inattention scores on the Conners' Parent Rating Scale were negatively correlated with absolute gamma.CONCLUSIONS:
These patients demonstrate the typical EEG profile in the eyes-closed resting state, over the delta, theta, alpha and beta bands, associated with AD/HD. In addition, compared with controls, they demonstrate reduced absolute and relative gamma activity. These differences appear to contribute importantly to their dysfunctional stimulus processing, and impact their behavioural outcomes.SIGNIFICANCE:
This resting-state study extends the well-established fast-wave EEG deficits in children with AD/HD to the gamma band, and links that to increased inattention, which is of special importance in understanding their cognitive-processing problems.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Descanso
/
Transtorno do Deficit de Atenção com Hiperatividade
/
Eletroencefalografia
Tipo de estudo:
Diagnostic_studies
Limite:
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Clin Neurophysiol
Assunto da revista:
NEUROLOGIA
/
PSICOFISIOLOGIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Austrália