Cloned antigens from Plasmodium falciparum as malaria vaccine candidates.
Behring Inst Mitt
; (88): 142-6, 1991 Feb.
Article
em En
| MEDLINE
| ID: mdl-2049031
ABSTRACT
The problems of genetic polymorphism and poor immunogenicity of malaria vaccine candidates are discussed, with emphasis on the Circumsporozoite (CS) and p190 proteins of Plasmodium falciparum. It may be possible to use conserved regions of these proteins to raise protective immune responses against non-polymorphic determinants. Better adjuvants or delivery systems will be a critical factor in development of an effective vaccine.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmodium falciparum
/
Vacinas Sintéticas
/
Malária
/
Antígenos de Protozoários
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Behring Inst Mitt
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Suíça