Ranitidine interference with the monoclonal EMIT d.a.u. amphetamine/methamphetamine immunoassay.
J Anal Toxicol
; 15(2): 101-3, 1991.
Article
em En
| MEDLINE
| ID: mdl-2051743
ABSTRACT
The interference of ranitidine with the monoclonal EMIT d.a.u. amphetamine/methamphetamine immunoassay (ME) was investigated. Urine specimens collected from 23 patients receiving 150-300 mg of ranitidine daily were found to contain 7-271 mg/L of the drug when analyzed by Remedi automated high pressure liquid chromatography. Only patient specimens and urine samples with ranitidine added at concentrations greater than 91 mg/L gave false positive ME results. Of the 63 patient urine samples analyzed by ME, 12 gave false positive results. All false positive results occurred in the first or second void after ingestion. No false positive results occurred with the polyclonal EMIT d.a.u. amphetamine or TDx amphetamine/methamphetamine II assays.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ranitidina
/
Anfetamina
/
Metanfetamina
/
Anticorpos Monoclonais
Limite:
Humans
Idioma:
En
Revista:
J Anal Toxicol
Ano de publicação:
1991
Tipo de documento:
Article