ODmixed: a tool to obtain optimal designs for heterogeneous longitudinal studies with dropout.
Comput Methods Programs Biomed
; 101(1): 62-71, 2011 Jan.
Article
em En
| MEDLINE
| ID: mdl-20541830
ABSTRACT
ODMixed is a computer program to obtain optimal designs for linear mixed models of longitudinal studies. These designs account for heterogeneous correlated errors and for data with dropout. Designs are compared by using relative efficiencies, e.g., between a D-optimal design for homogeneous data and another for heterogeneous data or between a D-optimal design for complete data against another that optimizes designs when data is missing at random. Two examples are worked out to illustrate how researchers could use this computer program to profit of optimal design theory at the planning stage of longitudinal studies.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Modelos Lineares
Tipo de estudo:
Observational_studies
Idioma:
En
Revista:
Comput Methods Programs Biomed
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Holanda