Amino acids and peptides. XIII. Synthetic studies on N-terminal tripeptide amide analogs of fibrin alpha-chain.
Chem Pharm Bull (Tokyo)
; 39(3): 584-9, 1991 Mar.
Article
em En
| MEDLINE
| ID: mdl-2070440
ABSTRACT
N-Terminal tripeptide analogs of fibrin alpha-chain were synthesized and their inhibitory effect on fibrinogen/thrombin clotting was examined. A new water-soluble active ester, 3-pyridinium ester, was used for the synthesis. Among the synthetic peptides, H-Gly-Pro-Arg-hexamethyleneimine exhibited the highest inhibitory effect on fibrinogen-thrombin clotting.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Fibrina
Idioma:
En
Revista:
Chem Pharm Bull (Tokyo)
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Japão