Review of the use of the glutamate antagonist riluzole in psychiatric disorders and a description of recent use in childhood obsessive-compulsive disorder.
J Child Adolesc Psychopharmacol
; 20(4): 309-15, 2010 Aug.
Article
em En
| MEDLINE
| ID: mdl-20807069
ABSTRACT
The antiglutamatergic drug riluzole (Rilutek) is presently being used off label in the treatment of psychiatric conditions in adult patients and, increasingly, in children. This article briefly reviews the pharmacology of this drug and its current investigative and clinical uses and adverse effects. It also reports on our experience to date in the study of the drug in children, with emphasis on adverse effects noted so far in these younger patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Riluzol
/
Transtornos Mentais
/
Transtorno Obsessivo-Compulsivo
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Animals
/
Child
/
Humans
Idioma:
En
Revista:
J Child Adolesc Psychopharmacol
Assunto da revista:
PEDIATRIA
/
PSICOFARMACOLOGIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos