Race and gender are not independent risk factors of allograft loss after kidney transplantation.

ABSTRACT

BACKGROUND: Little is known about the impact of gender on kidney allograft survival in black recipients. METHODS: A total of 805 kidney transplant recipients were reviewed retrospectively. RESULTS: All blacks compared with all whites had significantly reduced graft survival at 1, 2, and 3 years (89%, 84%, 82% vs 93%, 89%, 87%, respectively, log-rank P = .03). After stratification by race and gender, black females showed the worst graft survival. When black females were excluded, allograft survival between black males and all whites were similar. Black females carried more risk factors for graft loss. Compared with all others, the unadjusted hazard ratio of graft loss for black females was 1.67 (P < .01; 95% confidence interval, 1.15-2.43), but the adjusted hazard ratio was 1.47 (P = .07, 95% confidence interval, .98-2.23). CONCLUSIONS: Race and gender in a multivariate analysis are not statistically significant independent risk factors for poor allograft outcomes.