[Phenol constituents of Pachysandra terminalis and their antioxidant activity].
Zhongguo Zhong Yao Za Zhi
; 35(14): 1820-3, 2010 Jul.
Article
em Zh
| MEDLINE
| ID: mdl-20939276
ABSTRACT
OBJECTIVE:
To study the phenol constituents from Pachysandra terminalis and their antioxidant activities.METHOD:
Constituent isolation and purification was carried by repeated column chromatography (silica gel, Toyopearl HW-40 and preparative HPLC), and their structures were elucidated on the basis of spectral data analysis. DPPH method was used to evaluate the free radical scavenging activity of the isolated compounds.RESULT:
Nine phenol compounds (1-9) were isolated and their structures were identified as follow p-hydroxybenzaldehyde (1), vanillin (2), 1-(4-hydroxy-3-methoxyphenyl) -ethanone (3), syringaldehyde (4), salicylic acid (5), p-hydroxybenzoic acid (6), ferulic acid (7), 2,3,4-trihydroxybenzoic acid (8), 3,4-dihydroxybenzoic acid (9). The isolated compounds showed obviously antioxidant activity. At the concentration of 50 micromol x L(-1), compounds 7-9 revealed DPPH free radical scavenging rates were 87.8%, 97.8% and 92%, respectively.CONCLUSION:
Compounds 1-9 were isolated from this genus for the first time. They showed the significant antioxidant activity.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenóis
/
Extratos Vegetais
/
Pachysandra
/
Antioxidantes
Idioma:
Zh
Revista:
Zhongguo Zhong Yao Za Zhi
Assunto da revista:
FARMACOLOGIA
/
TERAPIAS COMPLEMENTARES
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
China