[Generalized status epilepticus after ingestion of ibuprofen (Brufen), disclosing systemic lupus erythematosus]. / Etat de mal comitial généralisé après prise d'ibuprofène (Brufen), révélateur d'un lupus érythémateux disséminé.

We report a case of aseptic meningoencephalitis induced by ibuprofen (Brufen) in a 24-year old unmarried woman with unrecognized systemic lupus erythematosus. The neurological manifestations induced by ibuprofen revealed the systemic disease. Clinicians confronted with aseptic meningitis or meningoencephalitis developed after treatment with a non-steroidal anti-inflammatory drug, notably ibuprofen, should investigate for systemic disease.