Dependence as a unifying construct in defining Alzheimer's disease severity.
Alzheimers Dement
; 6(6): 482-93, 2010 Nov.
Article
em En
| MEDLINE
| ID: mdl-21044778
ABSTRACT
This article reviews measures of Alzheimer's disease (AD) progression in relation to patient dependence and offers a unifying conceptual framework for dependence in AD. Clinicians typically characterize AD by symptomatic impairments in three domains cognition, function, and behavior. From a patient's perspective, changes in these domains, individually and in concert, ultimately lead to increased dependence and loss of autonomy. Examples of dependence in AD range from a need for reminders (early AD) to requiring safety supervision and assistance with basic functions (late AD). Published literature has focused on the clinical domains as somewhat separate constructs and has given limited attention to the concept of patient dependence as a descriptor of AD progression. This article presents the concept of dependence on others for care needs as a potential method for translating the effect of changes in cognition, function, and behavior into a more holistic, transparent description of AD progression.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Índice de Gravidade de Doença
/
Dependência Psicológica
/
Avaliação da Deficiência
/
Doença de Alzheimer
Limite:
Aged
/
Aged80
/
Humans
/
Middle aged
Idioma:
En
Revista:
Alzheimers Dement
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos