Occurrence of hydrin 2 (vasotocinyl-Gly), a new hydroosmotic neurohypophyseal peptide, in secretory granules isolated from the frog (Rana esculenta) neurointermediate pituitary.
Neuroendocrinology
; 51(2): 233-6, 1990 Feb.
Article
em En
| MEDLINE
| ID: mdl-2106101
ABSTRACT
Neurohypophyseal secretory granules have been purified from the frog (Rana esculenta) neurointermediate pituitary gland by sucrose gradient centrifugation, and their polypeptide content has been analyzed by reverse-phase high-pressure liquid chromatography. Aside from vasotocin, mesotocin, and their associated neurophysins, hydrin 2 (vasotocinyl-Gly), previously identified in hydrochloric acid extracts, has been recognized. This finding supports the previous suggestion that hydrin 2, a peptide active on the water permeability of frog bladder and frog skin, is a secreted hormone involved in osmoregulation specific to amphibians. Hydrin 2 has not been found in neurosecretory granules of birds such as the goose.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neuro-Hipófise
/
Vasotocina
/
Grânulos Citoplasmáticos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Neuroendocrinology
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
França