Comparison of a static and a dynamic in vitro model to estimate the bioaccessibility of As, Cd, Pb and Hg from food reference materials Fucus sp. (IAEA-140/TM) and Lobster hepatopancreas (TORT-2).
Sci Total Environ
; 409(3): 604-11, 2011 Jan 01.
Article
em En
| MEDLINE
| ID: mdl-21109290
ABSTRACT
Bioaccessibility, the fraction of an element solubilized during gastrointestinal digestion and available for absorption, is a factor that should be considered when evaluating the health risk of contaminants from food. Static and dynamic models that mimic human physiological conditions have been used to evaluate bioaccessibility. This preliminary study compares the bioaccessibility of arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg) in two food certified reference materials (CRMs) (seaweed Fucus sp., IAEA-140/TM; Lobster hepatopancreas TORT-2), using two in vitro gastrointestinal digestion methods:
a static method (SM) and a dynamic multicompartment method (TIM-1). There are significant differences (p<0.05) between the bioaccessible values of As, Cd, Pb and Hg obtained by SM and TIM-1 in the two CRMs. The specific form in which the elements studied are present in the CRM may help to explain the bioaccessibility values obtained.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arsênio
/
Poluentes Químicos da Água
/
Metais Pesados
/
Hepatopâncreas
/
Fucus
/
Nephropidae
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Sci Total Environ
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Espanha