Intralymphatic granulomas as a pathogenic factor in cheilitis granulomatosa/Melkersson-Rosenthal syndrome: report of a case with immunohistochemical and molecular studies.
Am J Dermatopathol
; 33(6): 594-8, 2011 Aug.
Article
em En
| MEDLINE
| ID: mdl-21317610
ABSTRACT
Orofacial granulomatosis, an uncommon immunologically mediated disorder, includes cheilitis granulomatosa and Melkersson-Rosenthal syndrome. It is clinically characterized by recurrent or persistent swelling of the orofacial tissues with a spectrum of other orofacial features and sometimes with neurological symptoms. The pathological findings are varied but are often characterized by the presence of noncaseating granuloma. We present a new case of orofacial granulomatosis with unusual histopathological findings, namely, intralymphatic granulomas. These may be the cause of the tissue edema. We demonstrated, by immunohistochemical studies, the lymphatic nature of the vessels affected by the granulomatous process.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Queilite
/
Vasos Linfáticos
/
Granuloma
/
Síndrome de Melkersson-Rosenthal
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Am J Dermatopathol
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Espanha