The influence of retinal illuminance on L- and M-cone driven electroretinograms.

ABSTRACT

The electroretinographic response to L- and M-cone isolating stimuli was measured at different luminance levels to study the effect of retinal illuminance on amplitude and phase, and how this may influence estimates of LM ratios in the retina. It was found that the amplitude of L- and M-cone driven responses increases differently with increasing retinal illuminance L-cone responses increase more quickly than those of M-cones. The LM ratio does not change strongly with retinal illuminance. The phase of both L- and M-cone driven responses advances with increasing retinal illuminance. There is considerable interindividual variability in the phase difference between the two, but generally M-cone driven responses are phase advanced.