Elevated amygdala response to faces following early deprivation.
Dev Sci
; 14(2): 190-204, 2011 Mar.
Article
em En
| MEDLINE
| ID: mdl-21399712
ABSTRACT
A functional neuroimaging study examined the long-term neural correlates of early adverse rearing conditions in humans as they relate to socio-emotional development. Previously institutionalized (PI) children and a same-aged comparison group were scanned using functional magnetic resonance imaging (fMRI) while performing an Emotional Face Go/Nogo task. PI children showed heightened activity of the amygdala, a region that supports emotional learning and reactivity to emotional stimuli, and corresponding decreases in cortical regions that support perceptual and cognitive functions. Amygdala activity was associated with decreased eye-contact as measured by eye-tracking methods and during a live dyadic interaction. The association between early rearing environment and subsequent eye-contact was mediated by amygdala activity. These data support the hypothesis that early adversity alters human brain development in a way that can persist into childhood, and they offer insight into the socio-emotional disturbances in human behavior following early adversity.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Desenvolvimento da Personalidade
/
Criança Institucionalizada
/
Expressão Facial
/
Tonsila do Cerebelo
Limite:
Adolescent
/
Child
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Child, preschool
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Female
/
Humans
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Male
Idioma:
En
Revista:
Dev Sci
Assunto da revista:
PSICOLOGIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos