Your browser doesn't support javascript.
loading
Sunscreen products: what do they protect us from?
Couteau, C; Couteau, O; Alami-El Boury, S; Coiffard, L J M.
Afiliação
  • Couteau C; Université de Nantes, Nantes Atlantique Universités, LPiC, MMS, EA2160, Faculty of Pharmacy, 1 rue G. Veil-BP 53508, Nantes, F-44000 France.
Int J Pharm ; 415(1-2): 181-4, 2011 Aug 30.
Article em En | MEDLINE | ID: mdl-21669263
ABSTRACT
Whereas for fifty or so years acquiring a tan has been the trend for aesthetic reasons relating to current beauty criteria, the health authorities are now advocating vigilance in this area, prompted by the knowledge of the harmful effects of the sun, especially from its ultra-violet rays. In the European Union, sunscreen products are considered cosmetics and tests on their effectiveness can be performed in vivo or in vitro to determine four effectiveness indicators the SPF (Sun Protection Factor), the PF-UVA (UVA Protection Factor), the SPF/PF-UVA ratio and the critical wave length. It is the erythemal SPF which is measured in the vast majority of cases it can therefore be confirmed that sunscreen products protect us from sunburn under good conditions of use. We thought it would be interesting to calculate other indicators to assess protection against non-melanoma skin cancers (NMSC) and to quantify the effectiveness of the product against UVA1 or UVA2. To characterize the products tested, we have determined in vitro different SPF and PF-UVA values, by using not just the erythemal weighting factor but also the weighting factor relating to the non-melanocytic skin cancer (SPF(cnm) and PF-UVA(cnm)), by getting away from any weighting factor (SPF(m) and PF-UVA(m)) and lastly, by varying the integration limits to quantify the effectiveness of the tested product in the UVB (290-320 nm), UVA1 (340-400 nm) and UVA2 320-340 nm) fields. In this way, and using these new indicators, we have been able to qualify eleven commercial products-ten cosmetic products and one medical device. It can be interesting to take into account the non-melanocytic skin cancer protection in order to qualify the sunscreen products.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Queimadura Solar / Protetores Solares / Raios Ultravioleta / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int J Pharm Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Queimadura Solar / Protetores Solares / Raios Ultravioleta / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int J Pharm Ano de publicação: 2011 Tipo de documento: Article