Pathologic findings and toxin identification in cyanobacterial (Nodularia spumigena) intoxication in a dog.
Vet Pathol
; 49(5): 755-9, 2012 Sep.
Article
em En
| MEDLINE
| ID: mdl-21825312
ABSTRACT
A 3-year-old Cairn Terrier dog that had been in contact with sea water containing cyanobacteria (blue-green algae) was euthanized because of acute hepatic failure and anuria after a 5-day illness. Histologic findings included lytic and hemorrhagic centrilobular hepatocellular necrosis and renal tubular necrosis. The cyanotoxin nodularin was detected in liver and kidney by high-performance liquid chromatography-mass spectrometry. Nodularin is a potent hepatotoxin produced by the algal species Nodularia spumigena. The intensity of algal blooms has increased during the past decades in the Baltic Sea region, thus increasing the risk for intoxications in domestic and wild animals. The authors describe the pathologic findings of cyanobacterial toxicosis in a dog with direct identification of the toxin from organ samples.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anuria
/
Peptídeos Cíclicos
/
Falência Hepática Aguda
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Nodularia
/
Doenças do Cão
/
Necrose do Córtex Renal
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
Vet Pathol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Finlândia