Antimicrobial activities of sesquiterpene lactones and inositol derivatives from Hymenoxys robusta.
Phytochemistry
; 72(18): 2413-8, 2011 Dec.
Article
em En
| MEDLINE
| ID: mdl-21963130
ABSTRACT
Six compounds from the aerial parts of the Argentinean plant Hymenoxys robusta (Rusby) Parker were isolated and their structures elucidated using extensive spectroscopic analyses. These compounds comprise two inositol derivatives and four 3,4-seco-pseudoguaianolides, including vermeerin. Bioactivity assays of these compounds against bacterial and fungal pathogens showed that only vermeerin possessed antimicrobial activity specific against Staphylococcus aureus, and showed no toxicity when exposed to human-derived macrophages.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sesquiterpenos
/
Asteraceae
/
Inositol
/
Lactonas
/
Anti-Infecciosos
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Argentina